Bioprospecting of Natural Products Associated with Microorganisms of Simmondsia chinensis : (Record no. 7162)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 08508nam a2200457 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-NbEJU |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250220154505.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250220b2024 ua | m||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-NbEJU |
| Language of cataloging | eng |
| Transcribing agency | EG-NbEJU |
| Modifying agency | EG-NbEJU |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| Language code of summary or abstract | ara |
| 050 ## - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | EPE PhD. 2025 |
| Item number | 01 |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Elbakary , Mustafa Fathy Mustafa , |
| 245 10 - TITLE STATEMENT | |
| Title | Bioprospecting of Natural Products Associated with Microorganisms of Simmondsia chinensis : |
| Remainder of title | A Thesis Submitted to the Institute of Basic and Applied Science : Egypt-Japan University of Science and Technology (E-JUST) : In Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy In Biotechnology / |
| Statement of responsibility, etc. | by Mustafa Fathy Mustafa Elbakary ; Supervisor Committee Associate Prof. Dr. Sherif Hammad - PharmD - E-JUST , Prof. Hesham Soliman - Pharm D - E-JUST , Prof. Sameh Heikal M.Youseif - Microbiology lab. - National Gene Bank - Agricultural Research Center ; Examination Committee Associate Prof. Dr. Sherif Hammad - PharmD - E-JUST , Prof. Hesham Soliman - Pharm D - E-JUST , Prof. Dr. Lotfy Diab Ismail - Faculty of Pharmacy - Al-Azhar University , Prof. Dr. Mohamed Emara - Faculty of Pharmacy - Helwan University<br/><br/> |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | استجلاء النواتج الطبيعية المصاحبة للكائنات الدقيقة في نبات الجوجوبا : <br/> |
| Remainder of title | رسالة علمية مقدمة إلى معهد العلوم الأساسية و التطبيقية : الجامعة المصرية اليابانية للعلوم و التكنولوجيا كاستيفاء جزئي لمتطلبات الحصول على درجة ( دكتوراه الفلسفة) في علم البيوتكنولوجي / إعداد مصطفى فتحي مصطفى البقري ; لجنة الاشراف على الرسالة أ . م . د / شريف فؤاد حماد - فارم دي - الجامعة المصرية اليابانية للعلوم و التكنولوجيا , أ . د . هشام سليمان - فارم دي - الجامعة المصرية اليابانية للعلوم و التكنولوجيا , ا . د . سامح هيكل - قسم الميكروبيولوجي - البنك القومي للجينات - مركز البحوث الزراعية ; لجنة المناقشة و الحكم على الرسالة أ . م . د / شريف فؤاد حماد - فارم دي - الجامعة المصرية اليابانية للعلوم و التكنولوجيا , أ . د . هشام سليمان - فارم دي - الجامعة المصرية اليابانية للعلوم و التكنولوجيا , أ . د / لطفي دياب اسماعيل - كلية الصيدلة - جامعة الأزهر , ا . د / محمد عمارة - كلية الصيدلة - جامعة حلوان<br/><br/> |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Alexandria : |
| Name of publisher, distributor, etc. | Mustafa Fathy Mustafa Elbakary |
| Date of publication, distribution, etc. | 2024 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 109 leaves ; |
| Dimensions | 30 cm |
| 500 ## - GENERAL NOTE | |
| General note | Includes a title page in Arabic |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) |
| Degree type | Doctoral |
| Name of granting institution | Egypt - Japan University of Science and Technology (E-JUST) - Basic and Applied Science (BAS) Institute - Biotechnology Department |
| Year degree granted | 2025 |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc. note | Includes bibliographical references |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Jojoba shrubs as medicinal plants are cultivated in arid and semiarid lands and racterized by tolerance to drought, salinity, and high temperatures Microorganisms associated h such plants are attributed to plant growth-promoting (PGP) and the production of bioactive npounds with medical applications Previous studies showed the importance of jojoba as jojoba in the agricultural field ; however, no prior study discussed the role of jojoba associated croorganisms in reflecting plant health , biocontrol and exploring their production for bioactive npounds Here , the culture-independent and culture-dependent approaches were performed to dy the diversity of the jojoba-associated microorganisms The Internal Transcribed Spacer (ITS) tagenome analysis revealed the existence of four fungal phyla : Ascomycota , Aphelidiomycota , sidiomycota, and Mortierellomycota The phylum Ascomycota was the most common and had e highest relative abundance in soil, root, branch, and fruit samples (59.7%, 50.7%, 49.8%, and 1.4%, respectively) Alternaria was the most abundant genus in aboveground tissues : branch 3.7%) and fruit (32.1%), while the genus Discosia had the highest abundance in the underground mples: soil (24%) and root (30.7 %) Furthermore , the analysis of FUNGuild revealed the bundance of symbiotrophs over other trophic modes , and the guild of endophytes was commonly ssigned in all samples For the analysis of 165 metagenome, the major phyla were Cyanobacteria , roteobacteria , and Actinobacteria At the level of genus, Sphingobium was abundant in soil amples (6%) , while Calothrix was abundant in all the inside jojoba's tissues (78.5% for roots, 5.5% for branches, 92.4% for leaves , and 86% for fruits). For the culture dependent method , a >tal of 66 isolates were isolated , identified , and screened for their chitinolytic, antagonist activity gainst three phytopathogenic fungi (Fusarium oxysporum , Alternaria alternata and Rhizoctonia olani) and antibacterial activity Therefore , 12 strains were selected and molecularly identified Based on ITS and 16S rRNA sequence analysis , the selected potent isolates were molecularly dentified as Aspergillus stellatus EJ-JFF3 , Aspergillus flavus EJ-JFF4 , Stilbocrea sp. EJ-JLF1 Fusarium solani EJ-JRF3 , Amesia atrobrunnea EJ-JSF4 , Bacillus velezensis EJ-JBBI , Bacillus pumilus EJ-JBB3, Enterobacter sp. EJ-JFB12, Psychrobacter sp. EJ-JSB4, Bacillus amyloliquefaciens EJ-JBA2 , Bacillus subtilis EJ-JRA4 , Streptomyces sp. EJ-JSA3 The endophyte strain A. flavus EJ-JFF4 exhibited the highest chitinolytic activity (9 Enzyme Index) and antagonistic potential against Fusarium oxysporum , Alternaria alternata , and Rhizoctonia solani |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | إن النباتات الطبية و البرية غنية بالكائنات الحية الدقيقة المرتبطة بها و التي يمكن أن تنتج مركبات نشطة بيولوجيا مختلفة و تحتوي شجيرات الجوجوبا على كائنات حية دقيقة مختلفة (بكتيريا، وبكتيريا أكتينو بكتيرية، وفطريات) أظهرت نشاطاً في تعزيز نمو النبات (للأغراض الزراعية) وأنشطة مضادة للبكتيريا و مضادة للسرطان (للأغراض الطبية) و قد أظهرت سلالة الرشاشة الصفراء JFF4. سلالة قوية لاستخدامها كعامل مكافحة حيوية كما أنه يمكن استخدام سلالة-Bacillas pumilur El BB3 و Bacillus anylalolignefaciens El-BA2 و Streptomyces sp. El-JSA3 كمصدر لإنتاج المضادات الحيوية كما أنه يمكن ايضا استخدام سلالات Bacillus any laloliquefaciens El- Bacillas panilas El-B33 BA2لإنتاج مستقلبات يمكن استخدامها كأدوية مضادة للسرطان ولمزيد من العمل، يوصى بتطوير تقييم سلالة Aspergillus fans ElJFF في تجارب الصوب البلاستيكية ثم التجارب الحقلية بالإضافة إلى ذلك، يوصى بتقييم المركبات التنقية المعزولة من المستخلصات البكتيرية الخام في المختبر ثم إجراء التجارب على حيوانات التجارب تمهيدا لاعتمادها واستخدامها بين البشر |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as a digital file (for more information please check our Digital Repository) |
| 590 ## - LOCAL NOTE (RLIN) | |
| Local note | AnD |
| Provenance (VM) [OBSOLETE] | ACM |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hammad , Sherif , |
| Relator term | Supervisor |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Soliman , Hesham , |
| Relator term | co-Supervisor |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Youseif , Sameh Heikal M. , |
| Relator term | co-Supervisor |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hammad , Sherif , |
| Relator term | Examinator |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Soliman , Hesham , |
| Relator term | co-Examinator |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ismail , Lotfy Diab , |
| Relator term | co-Examinator |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Emara , Mohamed , |
| Relator term | co-Examinator |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | حماد , شريف , |
| Relator term | مشرف |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | سليمان , هشام , |
| Relator term | مشرف مساعد |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | هيكل , سامح , |
| Relator term | مشرف مساعد |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | حماد , شريف , |
| Relator term | مناقش |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | سليمان , هشام , |
| Relator term | مناقش مساعد |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | اسماعيل , لطفي دياب , |
| Relator term | مناقش مساعد |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | عمارة , محمد , |
| Relator term | مناقش مساعد |
| 901 ## - Cataloger information | |
| Cataloger Name | HaGeR |
| 902 ## - PDF File name | |
| PDF File name | EJUST_1702_ (3) |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Library of Congress Classification |
| Suppress in OPAC | No |
| Koha item type | Dissertations |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Date acquired | Total checkouts | Full call number | Barcode | Date last seen | Copy number | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Library of Congress Classification | Fayza Aboulnaga Central Library | مكتبة فايزة أبو النجا المركزية بالحرم الجامعي | Fayza Aboulnaga Central Library | مكتبة فايزة أبو النجا المركزية بالحرم الجامعي | 02/20/2025 | EPE PhD. 2025 01 | 10014208 | 02/20/2025 | C. 1 | 02/20/2025 | Dissertations |