TY  - BOOK
AU  - Beckerman ,Martin
TI  - Molecular and cellular signaling / 
T2  - Biological and medical physics, biomedical engineering,
SN  - 0387221301 (alk. paper)
AV  - QP517.C45 B43 2005
PY  - 2005///
CY  - New York
PB  - Springer , 
KW  - Cellular signal transduction
KW  - LCSH
KW  - Biochemistry, general
KW  - Biophysics
KW  - Cell Biology
N1  - Includes bibliographical references and index
N2  - A small number of signaling pathways, no more than a dozen or so, form a control layer that is responsible for all signaling in and between cells of the human body. The signaling proteins belonging to the control layer determine what kinds of cells are made during development and how they function during adult life. Malfunctions in the proteins belonging to the control layer are responsible for a host of human diseases ranging from neurological disorders to cancers. Most drugs target components in the control layer, and difficulties in drug design are intimately related to the architecture of the control layer
ER  -