000			01596cam a22003134a 4500
003			EG-NbEJU
005			20240516114010.0
008			040722t2005 nyua grb 001 0 eng
010			_a2004052556
020			_a0387221301 (alk. paper)
020			_a9780387221304
040			_aDLC _cEG-NbEJU _dEG-NbEJU _beng
041			_aeng
042			_apcc
050	0	0	_aQP517.C45 _bB43 2005
100	1		_aBeckerman , Martin
245	1	0	_aMolecular and cellular signaling / _c[by] : Martin Beckerman
260			_aNew York : _bSpringer , _c©2005
300			_axxxiv , 574 p. : _billustrations ; _c24 cm.
490	0		_aBiological and medical physics, biomedical engineering, _x1618-7210
504			_aIncludes bibliographical references and index.
520			_aA small number of signaling pathways, no more than a dozen or so, form a control layer that is responsible for all signaling in and between cells of the human body. The signaling proteins belonging to the control layer determine what kinds of cells are made during development and how they function during adult life. Malfunctions in the proteins belonging to the control layer are responsible for a host of human diseases ranging from neurological disorders to cancers. Most drugs target components in the control layer, and difficulties in drug design are intimately related to the architecture of the control layer
650		0	_aCellular signal transduction _2LCSH
650		0	_aBiochemistry, general _2LCSH
650		0	_aBiophysics _xCell Biology _2LCSH
901			_asara sorur
902			_aENG_03_(1004)
942			_2lcc _cBK
999			_c3176 _d3176